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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHAT
All Species:
4.85
Human Site:
S377
Identified Species:
8.89
UniProt:
P28329
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28329
NP_066266.3
748
82536
S377
K
D
S
T
N
R
D
S
L
D
M
I
E
R
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109211
626
70697
I279
N
R
D
S
V
R
S
I
Q
K
S
I
F
T
V
Dog
Lupus familis
XP_543902
686
76910
T339
G
G
V
D
L
N
D
T
N
R
A
L
Q
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q03059
641
71834
T294
G
T
G
D
L
S
D
T
H
R
A
L
Q
L
L
Rat
Rattus norvegicus
P32738
640
71845
T293
G
T
G
E
L
S
D
T
H
R
A
L
Q
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509108
643
72737
A296
A
G
E
E
L
T
D
A
N
M
A
M
Q
L
L
Chicken
Gallus gallus
Q90YJ9
640
72605
T293
S
G
V
E
L
N
D
T
N
M
A
L
Q
L
L
Frog
Xenopus laevis
Q7ZXE1
659
74538
E312
R
Q
K
L
L
D
N
E
N
E
E
A
L
A
K
Zebra Danio
Brachydanio rerio
B2ZGJ1
637
71821
R290
T
E
L
N
D
S
N
R
A
L
L
M
L
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07668
721
81310
G355
C
L
D
E
P
L
A
G
N
F
N
A
R
G
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P32756
627
71299
D280
V
V
C
L
D
M
E
D
P
I
D
Y
G
K
N
Sea Urchin
Strong. purpuratus
XP_001185550
675
75787
P328
P
P
P
E
V
G
K
P
I
D
S
D
D
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32796
670
77223
I323
S
Q
D
S
L
E
T
I
H
K
S
S
F
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
37.8
77.9
N.A.
74.7
74.7
N.A.
68.4
66
24
57
N.A.
37.5
N.A.
29.2
46.3
Protein Similarity:
100
N.A.
55.7
82.4
N.A.
79.1
79
N.A.
76.5
74
40.6
68.8
N.A.
56.1
N.A.
45.1
62.4
P-Site Identity:
100
N.A.
13.3
6.6
N.A.
6.6
6.6
N.A.
6.6
6.6
0
0
N.A.
0
N.A.
0
6.6
P-Site Similarity:
100
N.A.
20
26.6
N.A.
26.6
26.6
N.A.
26.6
26.6
20
33.3
N.A.
0
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
8
8
0
39
16
0
8
0
% A
% Cys:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
24
16
16
8
47
8
0
16
8
8
8
0
0
% D
% Glu:
0
8
8
39
0
8
8
8
0
8
8
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
16
0
8
% F
% Gly:
24
24
16
0
0
8
0
8
0
0
0
0
8
8
8
% G
% His:
0
0
0
0
0
0
0
0
24
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
16
8
8
0
16
0
0
0
% I
% Lys:
8
0
8
0
0
0
8
0
0
16
0
0
0
8
8
% K
% Leu:
0
8
8
16
54
8
0
0
8
8
8
31
16
39
47
% L
% Met:
0
0
0
0
0
8
0
0
0
16
8
16
0
8
0
% M
% Asn:
8
0
0
8
8
16
16
0
39
0
8
0
0
0
8
% N
% Pro:
8
8
8
0
8
0
0
8
8
0
0
0
0
0
8
% P
% Gln:
0
16
0
0
0
0
0
0
8
0
0
0
39
0
0
% Q
% Arg:
8
8
0
0
0
16
0
8
0
24
0
0
8
8
0
% R
% Ser:
16
0
8
16
0
24
8
8
0
0
24
8
0
0
0
% S
% Thr:
8
16
0
8
0
8
8
31
0
0
0
0
0
8
0
% T
% Val:
8
8
16
0
16
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _